{"id":141914,"date":"2013-05-23T19:30:44","date_gmt":"2013-05-23T19:30:44","guid":{"rendered":"https:\/\/staging2.simonw59.sg-host.com\/advancing-translational-research-with-the-semantic-web\/"},"modified":"2022-05-26T13:43:44","modified_gmt":"2022-05-26T13:43:44","slug":"advancing-translational-research-with-the-semantic-web","status":"publish","type":"post","link":"https:\/\/force11.org\/post\/advancing-translational-research-with-the-semantic-web\/","title":{"rendered":"Advancing translational research with the Semantic Web."},"content":{"rendered":"
\n

Authors: Ruttenberg, Alan
\n\tClark, Tim
\n\tBug, William
\n\tSamwald, Matthias
\n\tBodenreider, Olivier
\n\tChen, Helen
\n\tDoherty, Donald
\n\tForsberg, Kerstin
\n\tGao, Yong
\n\tKashyap, Vipul
\n\tKinoshita, June
\n\tLuciano, Joanne
\n\tMarshall, M Scott
\n\tOgbuji, Chimezie
\n\tRees, Jonathan
\n\tStephens, Susie
\n\tWong, Gwendolyn T
\n\tWu, Elizabeth
\n\tZaccagnini, Davide
\n\tHongsermeier, Tonya
\n\tNeumann, Eric
\n\tIvan Herman
\n\tCheung, Kei-Hoi<\/p>\n

BACKGROUND: A fundamental goal of the U.S. National Institute of Health (NIH) "Roadmap" is to strengthen Translational Research, defined as the movement of discoveries in basic research to application at the clinical level. A significant barrier to translational research is the lack of uniformly structured data across related biomedical domains. The Semantic Web is an extension of the current Web that enables navigation and meaningful use of digital resources by automatic processes. It is based on common formats that support aggregation and integration of data drawn from diverse sources. A variety of technologies have been built on this foundation that, together, support identifying, representing, and reasoning across a wide range of biomedical data. The Semantic Web Health Care and Life Sciences Interest Group (HCLSIG), set up within the framework of the World Wide Web Consortium, was launched to explore the application of these technologies in a variety of areas. Subgroups focus on making biomedical data available in RDF, working with biomedical ontologies, prototyping clinical decision support systems, working on drug safety and efficacy communication, and supporting disease researchers navigating and annotating the large amount of potentially relevant literature. RESULTS: We present a scenario that shows the value of the information environment the Semantic Web can support for aiding neuroscience researchers. We then report on several projects by members of the HCLSIG, in the process illustrating the range of Semantic Web technologies that have applications in areas of biomedicine. CONCLUSION: Semantic Web technologies present both promise and challenges. Current tools and standards are already adequate to implement components of the bench-to-bedside vision. On the other hand, these technologies are young. Gaps in standards and implementations still exist and adoption is limited by typical problems with early technology, such as the need for a critical mass of practitioners and installed base, and growing pains as the technology is scaled up. Still, the potential of interoperable knowledge sources for biomedicine, at the scale of the World Wide Web, merits continued work.<\/p>\n

Journal: BMC Bioinformatics 2007 vol 8 Suppl 3 pagination S2<\/p>\n

PMID: 17493285<\/p>\n

PMCID: 0<\/p>\n

ISSN: 1471-2105<\/p>\n<\/div>\n

Archive:<\/span> https:\/\/archive.force11.net\/node\/6391<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Authors: Ruttenberg, Alan Clark, Tim Bug, William Samwald, Matthias Bodenreider, Olivier Chen, Helen Doherty, Donald Forsberg, Kerstin Gao, Yong Kashyap, Vipul Kinoshita, June Luciano, Joanne Marshall, M Scott Ogbuji, Chimezie Rees, Jonathan Stephens, Susie Wong, Gwendolyn T Wu, Elizabeth Zaccagnini, Davide Hongsermeier, Tonya Neumann, Eric Ivan Herman Cheung, Kei-Hoi BACKGROUND: A fundamental goal of the … Read more<\/a><\/p>\n","protected":false},"author":205907,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[151],"tags":[],"force11":[],"blog_series":[],"working_group":[],"class_list":["post-141914","post","type-post","status-publish","format-standard","hentry","category-news"],"acf":[],"author_meta":{"display_name":"Tim Clark","author_link":"\/members\/tim-clark"},"featured_img":null,"coauthors":[],"tax_additional":{"categories":{"linked":["News<\/a>"],"unlinked":["News<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Posted 13 years ago","modified":"Updated 4 years ago"},"absolute_dates":{"created":"Posted on 23 May 2013","modified":"Updated on 26 May 2022"},"absolute_dates_time":{"created":"Posted on 23 May 2013 19:30","modified":"Updated on 26 May 2022 13:43"},"featured_img_caption":"","series_order":"","_links":{"self":[{"href":"https:\/\/force11.org\/wp-json\/wp\/v2\/posts\/141914","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/force11.org\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/force11.org\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/force11.org\/wp-json\/wp\/v2\/users\/205907"}],"replies":[{"embeddable":true,"href":"https:\/\/force11.org\/wp-json\/wp\/v2\/comments?post=141914"}],"version-history":[{"count":0,"href":"https:\/\/force11.org\/wp-json\/wp\/v2\/posts\/141914\/revisions"}],"wp:attachment":[{"href":"https:\/\/force11.org\/wp-json\/wp\/v2\/media?parent=141914"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/force11.org\/wp-json\/wp\/v2\/categories?post=141914"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/force11.org\/wp-json\/wp\/v2\/tags?post=141914"},{"taxonomy":"force11","embeddable":true,"href":"https:\/\/force11.org\/wp-json\/wp\/v2\/force11?post=141914"},{"taxonomy":"blog_series","embeddable":true,"href":"https:\/\/force11.org\/wp-json\/wp\/v2\/blog_series?post=141914"},{"taxonomy":"working_group","embeddable":true,"href":"https:\/\/force11.org\/wp-json\/wp\/v2\/working_group?post=141914"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}